![]() ![]() “ Amfetamin” By Wesalius – Own work (Public Domain) via Commons WikimediaĢ. The key difference between amphetamine and methamphetamine is that amphetamines are less potent than methamphetamines. The below infographic presents the differences between amphetamine and methamphetamine in tabular form for side-by-side comparison.Īmphetamine is a strong central nervous system stimulant that is useful in the treatment of attention deficit hyperactivity disorder (ADHD), narcolepsy, and obesity, while methamphetamine is a potent central nervous system stimulant that is useful in recreational drugs. They have similarities as well as some differences between them. What is the Difference Between Amphetamine and Methamphetamine?īoth amphetamines and methamphetamines are stimulant drugs. ![]() They make us more active and talkative.Both can cause intense pleasure or happiness.Amphetamine and methamphetamine are stimulant drugs.What are the Similarities Between Amphetamine and Methamphetamine? But a high dose can cause psychosis, breakdown of skeletal muscle, seizures, and bleeding in the brain. Excretion occurs primarily through the kidney.įurthermore, a low to moderate dose of this medication can elevate the mood, increase alertness, concentration, and energy in fatigued patients, reduce the appetite, and can promote weight loss. The elimination half-life can be given as 9 – 12 hours, and the duration of action is 8 – 12 hours. Moreover, the onset of action is 3 hours at peak when orally taken whereas it is less than 15 minutes in the intravenous administration. The protein binding ability varies widely. The bioavailability of methamphetamine is 67% when orally taken, while it is 100% when taken via the intravenous route. ![]() The medical route of administration for methamphetamine is oral (ingestion), while the recreational routes include oral, intravenous, intramuscular, subcutaneous, vapor inhalation, insufflation, rectal, and vaginal administration. Moreover, the addiction liability is high as well. The physical dependence liability of methamphetamine is negligible, while the psychological dependence liability is high. The chemical name of this compound is N-methylamphetmaine. ![]() The trade names of methamphetamine are Desoxyn and Methedrine. This exists as two enantiomers: D and L form.įigure 02: The Chemical Structure of Methamphetamine Methamphetamine is a potent central nervous system stimulant that is useful in recreational drugs and less commonly found as a second-line treatment for attention deficit hyperactivity disorder and obesity. Moreover, amphetamine is in the phenethylamine class, which is also the parent compound of its own structural class, “the substituted amphetamines.” This includes prominent substances, including bupropion, cathinone, MDMA, and methamphetamine. The melting point of this drug is 11.3 degrees Celsius while the boiling point is 203 degrees Celsius. The chirality of amphetamine can be described as a racemic mixture, and the density is 0.936 g/cm 3. The molar mass of this compound is 135.21 g/mol. The chemical formula of amphetamine is C 9H 13N. For the D enantiomer, the elimination half-life is 9 – 11 hours, and the elimination half-life of the L enantiomer is in the range of 11 – 14 hours. Primarily, the excretion of amphetamine happens through the renal route. The protein binding ability of this medication is 20%. The bioavailability of amphetamine can be given in the range of 75 – 100%. This drug can be described as a stimulant and an anorectic drug. Route of medical administration of amphetamine are oral and intravenous, but recreational administration may include oral, insufflation, rectal, and intramuscular means. The dependence liability and addiction liability of this medication are moderate. Its chemical name is alpha-methylphenethylamine. Figure 01: The Chemical Structure of AmphetamineĪmphetamine is also known by the trade names Evekeo and Adderall. ![]()
0 Comments
Leave a Reply.AuthorWrite something about yourself. No need to be fancy, just an overview. ArchivesCategories |